DIHYDROFOLATE-REDUCTASE GENE, POINT MUTATIONS, DRUG PRESSURE, PYRIMETHAMINE, RESISTANCE, FALCIPARUM, VIVAX
PUBLIC LIBRARY SCIENCE
PLOS ONE; vol.9 issue 4
The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.