DIHYDROFOLATE-REDUCTASE GENE; POINT MUTATIONS; DRUG PRESSURE; PYRIMETHAMINE; RESISTANCE; FALCIPARUM; VIVAX
PLOS ONE;PLoS One;03-Apr;2014;9;4
The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.