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Title: Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin m antibodies in Laos
Authors: Blacksell, SD; Smythe, L; Phetsouvanh, R; Dohnt, M; Hartskeerl, R; SymondS, M; Slack, A; Vongsouvath, M; Davong, V; Lattana, O; Phongmany, S; Keolouangkot, V; White, NJ; Day, NPJ; Newton, PN
Issue Date: 2006
Citation: Clin. Vaccine Immunol.;OCT;2006;13;10
Abstract: The diagnostic utility of immunochromatographic (Leptotek) and enzyme-linked immunosorbent assay (ELISA; Panbio) tests for the detection of Leptospira immunoglobulin M antibodies was assessed in febrile adults admitted in Vientiane, Laos. Both tests demonstrated poor diagnostic accuracy using admission serum (Leptotek sensitivity of 47.3% and specificity of 75.5%: ELISA sensitivity of 60.9% and specificity of 65.6%) compared to the Leptospira "gold standard" microscopic agglutination test.
ISSN: 1556-6811

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