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Title: A Novel Technique for Detecting Antibiotic-Resistant Typhoid from Rapid Diagnostic Tests
Authors: Fhogartaigh, CN; Dance, DAB; Davong, V; Tann, P; Phetsouvanh, R; Turner, P; Dittrich, S; Newton, PN
Keywords: ENTERICA SEROVAR TYPHI; REDUCED SUSCEPTIBILITY; CLINICAL-RESPONSE; DRUG-RESISTANCE; FILTER-PAPER; FLUOROQUINOLONES; AMPLIFICATION; FEVER; VITRO; ASIA
Issue Date: 2015
Publisher: J CLIN MICROBIOL
Citation: J. Clin. Microbiol.;MAY;2015;53;5
Abstract: Fluoroquinolone-resistant typhoid is increasing. An antigen-detecting rapid diagnotic test (RDT) can rapidly diagnose typhoid from blood cultures. A simple, inexpensive molecular technique performed with DNA from positive RDTs accurately identified gyrA mutations consistent with phenotypic susceptibility testing results. Field diagnosis combined with centralized molecular resistance testing could improve typhoid management and surveillance in low-resource settings.
URI: http://hdl.handle.net/11267/2358
ISSN: 0095-1137

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