A Novel Technique for Detecting Antibiotic-Resistant Typhoid from Rapid Diagnostic Tests

Title
A Novel Technique for Detecting Antibiotic-Resistant Typhoid from Rapid Diagnostic Tests
Authors
Fhogartaigh, CN; Dance, DAB; Davong, V; Tann, P; Phetsouvanh, R; Turner, P; Dittrich, S; Newton, PN
Keywords
ENTERICA SEROVAR TYPHI; REDUCED SUSCEPTIBILITY; CLINICAL-RESPONSE; DRUG-RESISTANCE; FILTER-PAPER; FLUOROQUINOLONES; AMPLIFICATION; FEVER; VITRO; ASIA
Issue Date
2015
Publisher
J CLIN MICROBIOL
Citation
J. Clin. Microbiol.;MAY;2015;53;5
Abstract
Fluoroquinolone-resistant typhoid is increasing. An antigen-detecting rapid diagnotic test (RDT) can rapidly diagnose typhoid from blood cultures. A simple, inexpensive molecular technique performed with DNA from positive RDTs accurately identified gyrA mutations consistent with phenotypic susceptibility testing results. Field diagnosis combined with centralized molecular resistance testing could improve typhoid management and surveillance in low-resource settings.
URI
http://hdl.handle.net/11267/2358
ISSN
0095-1137
Appears in Collections:
5.Mahosot Hospital > Journal articles
Files in This Item:

qrcode

Items in LAOSpace are protected by copyright, with all rights reserved, unless otherwise indicated.