A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos

Title
A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos
Authors
Mayxay, M; Phetsouvanh, R; Phompida, S; Newton, PN; Khanthavong, M; Vannachone, B; Brockman, A; White, NJ
Keywords
MARKERS
Issue Date
2003
Publisher
T ROY SOC TROP MED H
Citation
Trans. Roy. Soc. Trop. Med. Hyg.;MAY-JUN;2003;97;3
Abstract
Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure was high (CQ = 78%, RIII 46%; SP = 36%, RIII 15%). The treatment policy for uncomplicated P. falciparum malaria in Laos needs to be reviewed urgently.
URI
http://hdl.handle.net/11267/2389
ISSN
0035-9203
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5.Mahosot Hospital > Journal articles
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