Rickettsial infections and fever, Vientiane, Laos

Title
Rickettsial infections and fever, Vientiane, Laos
Authors
Phongmany, S; Rolain, JM; Phetsouvanh, R; Blacksell, SD; Soukkhaseum, V; Rasachack, B; Phiasakha, K; Soukkhaseum, S; Frichithavong, K; Chu, V; Keolouangkhot, V; Martinez-Aussel, B; Chang, K; Darasavath, C; Rattanavong, O; Sisouphone, S; Mayxay, M; Vidamaly, S; Parola, P; Thammavong, C; Heuangvongsy, M; Syhavong, B; Raoult, D; White, NJ; Newton, PN
Keywords
SCRUB TYPHUS; MURINE TYPHUS; HELVETICA INFECTION; CLINICAL-FEATURES; THAILAND; DISEASES; AZITHROMYCIN; OPERATIONS; DIAGNOSIS; TRAVELER
Issue Date
2006
Publisher
EMERG INFECT DIS
Citation
Emerg. Infect. Dis;FEB;2006;12;2
Abstract
Rickettsial diseases have not been described previously from Laos, but in a prospective study, acute rickettsia[ infection was identified as the cause of fever in 115 (27%) of 427 adults with negative blood cultures admitted to Mahosot Hospital in Vientiane, Laos. The organisms identified by serologic analysis were Orientia tsutsugamushi (14.8%), Rickettsia typhi (9.6%), and spotted fever group rickettsia (2.6% [8 R. helvetica, 1 R. felis, 1 R. conorii subsp. indica, and 1 Rickettsia nullAT1null]). Patients with murine typhus had a lower frequency of peripheral lymphadenopathy than those with scrub typhus (3% vs. 46%, p < 0.001). Rickettsioses are an underrecognized cause of undifferentiated febrile illnesses among adults in Laos. This finding has implications for the local empiric treatment of fever.
URI
http://hdl.handle.net/11267/2426
ISSN
1080-6040
Appears in Collections:
5.Mahosot Hospital > Journal articles
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