Patterns and Risks of Trichinella Infection in Humans and Pigs in Northern Laos

Title
Patterns and Risks of Trichinella Infection in Humans and Pigs in Northern Laos
Authors
Conlan, JV; Vongxay, K; Khamlome, B; Gomez-Morales, MA; Pozio, E; Blacksell, SD; Fenwick, S; Thompson, RCA
Keywords
PAPUA-NEW-GUINEA; HUMAN TRICHINOSIS; PARASITIC INFECTIONS; SOUTHEAST-ASIA; OUTBREAK; IDENTIFICATION; CONSUMPTION; PROVINCE; ANIMALS
Issue Date
2014
Publisher
PLOS NEGLECT TROP D
Citation
Plos Neglect. Trop. Dis.;JUL;2014;8;7
Abstract
Several outbreaks of trichinellosis associated with the consumption of raw pork have occurred in Laos since 2004. This cross-sectional study was conducted in four provinces of northern Laos to investigate the seroepidemiology of trichinellosis in the human population and determine the prevalence and species of Trichinella infection in the domestic pig population. Serum samples and questionnaire data were obtained from 1419 individuals. Serum samples were tested for Trichinella antibodies by ELISA using larval excretory-secretory (ES) antigens and a subset of 68 positive samples were tested by western blot. The seroprevalence of Trichinella antibodies was 19.1% (95% confidence interval (CI) = 17.1-21.1%). The risk of having antibodies detected by ELISA using ES antigens increased with age, being of Lao-Tai ethnicity, living in Oudomxay province and being male. Tongue and diaphragm muscle samples were collected from 728 pigs and tested for Trichinella larvae by the artificial digestion method. Trichinella larvae were isolated from 15 pigs (2.1%) of which 13 were identified as T. spiralis by molecular typing; the species of the two remaining isolates could not be determined due to DNA degradation. Trichinella spp. are endemic in the domestic environment of northern Laos and targeted preventative health measures should be initiated to reduce the risk of further outbreaks occurring.
URI
http://hdl.handle.net/11267/2500
ISSN
1935-2735
Appears in Collections:
2.Ministry of Health > Journal articles
Files in This Item:

qrcode

Items in LAOSpace are protected by copyright, with all rights reserved, unless otherwise indicated.