Short Report Serological Investigations of Flavivirus Prevalence in Khammouane Province, Lao People's Democratic Republic, 2007-2008

Title
Short Report Serological Investigations of Flavivirus Prevalence in Khammouane Province, Lao People's Democratic Republic, 2007-2008
Authors
Hiscox, A; Winter, CH; Vongphrachanh, P; Sisouk, T; Somoulay, V; Phompida, S; Kaul, S; Sananikhom, P; Nguyen, TY; Paul, RE; Brev, P; Bryant, JE
Keywords
JAPANESE ENCEPHALITIS; SOUTHERN VIETNAM; VIRUS-INFECTION; RISK-FACTORS; DENGUE; SEROPREVALENCE
Issue Date
2010
Publisher
AM J TROP MED HYG
Citation
Am. J. Trop. Med. Hyg.;NOV;2010;83;5
Abstract
A large scale cross sectional seroprevalence study of dengue (DEN) and Japanese encephalitis (JE) was conducted in Khammouane province Lao PDR as part of the initial baseline health impact assessment of the Nam Theun 2 hydroelectric dam construction project Health surveys were performed between May 2007 and February 2008 with serum samples collected from healthy individuals involved in the resettlement program of 16 villages (total surveyed population 4,369) Hemagglutination inhibition assay using flavivirus antigens (DENV1 DENV3, and JEV) performed on 1,708 plasma specimens revealed 30 4% (519) cross-reactive positives and 10% (172) and 1 3% (22) positives to JEV or DENV, respectively Entomological surveys conducted during the rainy season of 2008 indicated the presence of com petent flavivirus vectors (Cain vishnut group and Acdes albopictus) although Aedes aegypti was not found Continued surveillance and investigation is warranted to assess the clinical disease burden of flaviviruses in this area that is undergoing rapid ecological and demographic change
URI
http://hdl.handle.net/11267/2556
ISSN
0002-9637
Appears in Collections:
2.Ministry of Health > Journal articles
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